Publications

Sackey-Aboagye B, Olsen AL, Mukherjee SM, Ventriglia A, Yokosaki Y, Greenbaum LE, Lee GY, Naga H, Wells RG. Fibronectin Extra Domain A Promotes Liver Sinusoid Repair following Hepatectomy. PLoS One 2016;14:e0163737. doi: 10.1037/journal.pone.0163737.

Waisbourd-Zinman O, Koh H,Tsai S, Lavrut P-M, Dang C, Zhao X, Pack M, Cave J, Hawes M, Koo KA, Porter JR, Wells RG. The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis via decreased glutathione and SOX17, Hepatology, 2016;64:880-93. doi: 10.1002/hep28599 (**See associated editorial**)

Wells RG. Location, location, location: cell-level mechanics in liver fibrosis. Hepatology, 2016;64:32-3. doi: 10.1002/hep.28519. 

Caliari SR, Perepelyuk M, Cosgrove BD, Tsai SJ, Lee GY, Mauck RL, Wells RG, Burdick JA. Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechano-transduction during myofibroblast activation. Sci Reports, 2016;6:21387. PMCID: PMC4764908.

Perepelyuk M, Chin L, Cao X, van Oosten A, Shenoy VB, Janmey PA, Wells RG. Normal and fibrotic rat livers demonstrate shear strain softening and compression stiffening: a model for soft tissue mechanics. PLoS One. 2016 Jan 6;11(1):e0146588. doi10.1371/journal.pone.0146588. eCollection 2016. PMCID:PMC4703410

Wells RG, Schwabe RF. Origin and function of myofibroblasts in the liver. Semin Liver Dis 2015;35:e1.

Wells RG. Portal fibroblasts in biliary fibrosis. Current Pathobiology Reports, 2014;2:185-190.

Muir AB, Dods K, Henry SJ, Benitez AJ, Lee D, Whelan KA, DeMarshall M, Hammer DA, Falk G, Wells RG, Spergel J, Nakagawa H, Wang ML. Eosinophilic esophagitis associated chemical and mechanical microenvironment shapes esophageal fibroblast behavior. J Pediatr Gastroenterol Nutr. 2015 Dec 30. 

Koo KA, Waisbourd-Zinman O, Wells RG, Pack M, Porter JR. Reactivity of biliatresone, a natural biliary toxin, with glutathione, histamine, and amino acids. Chem Res Toxicol. 2016;29:142. PMCID:PMC4757443

Koo K, Lorent K, Gong W, Windsor P, Whittaker S, Pack M, Wells RG, Porter J. Biliatresone, A Reactive Natural Toxin from Dysphania glomulifera and D. littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone. Chem Res in Toxicol 2015;28:1519-21. PMCID:PMC4755499

Lorent K, Gong W, Koo KA, Waisbourd-Zinman O, Karjoo S, Zhao X, Sealy I, Kettleborough RN, Stemple DL, Windsor PA, Whittaker SJ, Porter JR, Wells RG*, Pack M*. Identification of a plant isoflavonoid that causes biliary atresia. Sci Transl Med 2015;7:286ra67. PMCID:PMC4784984 (*co-corresponding authors; featured research highlight in Nature Reviews Gastroenterology & Hepatology)

Brisson BK, Mauldin EA, Lei W, Vogel LK, Power AM, Lo A, Dopkin D, Khanna C, Wells RG, Puré E, Volk SW. Type III collagen directs stromal organization and limits metastasis in a murine model of breast cancer. Am J Pathol 2015;185:1471-86

Wells RG. The portal fibroblast: not just a poor man’s stellate cell. Gastroenterology 2014;147:41-47.